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T Sorsa Selected Research

Tetracyclines

6/2010Doxycycline effects on serum bone biomarkers in post-menopausal women.
1/2002Inhibition of proteolytic, serpinolytic, and progelatinase-b activation activities of periodontopathogens by doxycycline and the non-antimicrobial chemically modified tetracycline derivatives.
8/2001A combination of a chemically modified doxycycline and a bisphosphonate synergistically inhibits endotoxin-induced periodontal breakdown in rats.
2/2001CMT-3, a non-antimicrobial tetracycline (TC), inhibits MT1-MMP activity: relevance to cancer.
5/2000Down-regulation of trypsinogen-2 expression by chemically modified tetracyclines: association with reduced cancer cell migration.

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T Sorsa Research Topics

Disease

22Periodontitis
10/2020 - 06/2001
14Inflammation (Inflammations)
01/2017 - 12/2000
11Chronic Periodontitis
01/2014 - 05/2000
9Periodontal Diseases (Periodontal Disease)
04/2018 - 12/2000
8Gingivitis
10/2020 - 03/2001
7Neoplasms (Cancer)
03/2009 - 04/2000
6Hemorrhage
10/2020 - 05/2000
5Carcinoma (Carcinomatosis)
03/2009 - 08/2000
5Neoplasm Metastasis (Metastasis)
11/2004 - 04/2000
4Periodontal Pocket (Periodontal Pockets)
10/2020 - 01/2004
4Cardiovascular Diseases (Cardiovascular Disease)
10/2017 - 10/2006
4Infections
06/2017 - 10/2004
4Bone Resorption
06/2010 - 06/2001
3Chronic Obstructive Pulmonary Disease (COPD)
06/2013 - 03/2001
3Necrosis
01/2010 - 06/2001
2Aggressive Periodontitis (Periodontosis)
12/2012 - 12/2000
2Type 2 Diabetes Mellitus (MODY)
07/2010 - 10/2000
2Asthma (Bronchial Asthma)
01/2010 - 01/2010
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/2009 - 05/2002
2Pain (Aches)
02/2006 - 04/2005
2Squamous Cell Carcinoma of Head and Neck
10/2005 - 05/2002
2Colonic Neoplasms (Colon Cancer)
02/2001 - 05/2000
2Rheumatoid Arthritis
06/2000 - 02/2000
1Pancreatitis
08/2021
1Bacterial Infections (Bacterial Infection)
10/2020
1Diabetic Nephropathies (Diabetic Nephropathy)
01/2017
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2017
1Rupture
12/2016
1Gingival Recession
08/2016
1Disseminated Intravascular Coagulation
02/2015
1Sepsis (Septicemia)
02/2015
1Myocardial Infarction
06/2012
1Abdominal Aortic Aneurysm
08/2010
1Atherosclerosis
08/2010
1Diabetes Mellitus
07/2010
1Deficiency Diseases (Deficiency Disease)
06/2010

Drug/Important Bio-Agent (IBA)

41Matrix Metalloproteinases (MMPs)IBA
08/2016 - 04/2000
24Matrix Metalloproteinase 8 (Neutrophil Collagenase)IBA
08/2021 - 05/2000
11Collagenases (Collagenase)FDA Link
04/2018 - 06/2000
11Peptide Hydrolases (Proteases)FDA Link
11/2017 - 05/2000
10Tissue Inhibitor of Metalloproteinase-1IBA
08/2016 - 07/2001
9Proteins (Proteins, Gene)FDA Link
06/2006 - 05/2000
8EnzymesIBA
10/2020 - 04/2000
8CytokinesIBA
11/2017 - 06/2001
7CollagenIBA
02/2012 - 12/2000
6Matrix Metalloproteinase 9 (Gelatinase B)IBA
03/2009 - 04/2000
6GelatinasesIBA
03/2009 - 10/2000
5TetracyclinesIBA
06/2010 - 05/2000
5Messenger RNA (mRNA)IBA
10/2004 - 05/2000
4Biomarkers (Surrogate Marker)IBA
08/2021 - 01/2010
4Pancreatic Elastase (Elastase)IBA
06/2012 - 05/2000
4Peroxidase (Myeloperoxidase)IBA
01/2011 - 08/2010
4Doxycycline (Periostat)FDA LinkGeneric
06/2010 - 05/2000
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2007 - 03/2001
3ImmunosorbentsIBA
10/2020 - 01/2010
3Leukocyte Elastase (Neutrophil Elastase)IBA
10/2020 - 03/2001
3Diphosphonates (Bisphosphonates)IBA
08/2001 - 06/2000
2Tuberculin (PPD)IBA
10/2020 - 04/2018
2Immunoglobulins (Immunoglobulin)IBA
01/2017 - 06/2001
2Immunoglobulin A (IgA)IBA
01/2017 - 10/2001
2Cathepsin GIBA
06/2012 - 09/2005
2Serine Proteases (Serine Protease)IBA
06/2012 - 05/2001
2LipopolysaccharidesIBA
02/2011 - 03/2002
2Interleukin-6 (Interleukin 6)IBA
01/2010 - 06/2001
2matrigelIBA
03/2009 - 02/2001
2Matrix Metalloproteinase 13IBA
11/2006 - 03/2002
2Tissue Inhibitor of Metalloproteinase-2IBA
10/2004 - 09/2001
2EndotoxinsIBA
03/2002 - 08/2001
2TrypsinIBA
05/2001 - 08/2000
1peptidoglycan recognition proteinIBA
10/2020
1InterleukinsIBA
10/2019
1ChymotrypsinFDA Link
11/2017
1Toll-Like Receptor 4IBA
11/2017
1Mannose-Binding Lectin (Mannan-Binding Lectin)IBA
06/2017
1EpitopesIBA
01/2017
1Leukocyte L1 Antigen Complex (Calgranulin)IBA
01/2017
1AntibodiesIBA
01/2017
1Lipoproteins (Lipoprotein)IBA
01/2017
1LipidsIBA
01/2017
1oxidized low density lipoproteinIBA
01/2017
1Volatile Fatty AcidsIBA
01/2017
1Alkaline PhosphataseIBA
01/2017
1CathelicidinsIBA
12/2016
1Interleukin-1beta (Interleukin 1 beta)IBA
08/2016
1Dacarbazine (DIC)FDA LinkGeneric
02/2015
1cyclopropapyrroloindoleIBA
09/2014
1Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA
06/2013
1Azithromycin (Zithromax)FDA LinkGeneric
12/2012
1CXC ChemokinesIBA
02/2011
1IsoenzymesIBA
11/2010
1enamel matrix proteinsIBA
06/2010
1TabletsIBA
06/2010
1SteroidsIBA
01/2010
1Interferon-gamma (Interferon, gamma)IBA
01/2010
1Budesonide (Pulmicort)FDA LinkGeneric
01/2010
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
01/2010
14- (4- dihexadecylaminostyryl)- N- methylpyridium (DiA)IBA
01/2010
1Hormones (Hormone)IBA
08/2009

Therapy/Procedure

9Therapeutics
12/2012 - 05/2000
1Oral Hygiene (Dental Hygiene)
01/2014